Spicy Cajun Chicken Fettuccine in Creamy Garlic Sauce

I love making Spicy Cajun Chicken Fettuccine when I want a comforting, flavorful pasta dish that combines spicy Cajun-seasoned chicken with a rich, creamy garlic sauce. It’s hearty, satisfying, and perfect for dinner any night of the week.

Why I’ll Love This Recipe

What I enjoy most is the bold Cajun spices paired with the smooth, garlicky cream sauce that coats every strand of fettuccine. The tender chicken adds protein and a spicy kick, making this dish both indulgent and balanced. It’s a crowd-pleaser that I can whip up quickly.

ingredients

(Here’s a tip: Check out the full list of ingredients and measurements in the recipe card below.)
• boneless, skinless chicken breasts or thighs
• Cajun seasoning
• fettuccine pasta
• butter
• garlic, minced
• heavy cream
• grated Parmesan cheese
• olive oil
• salt and pepper
• fresh parsley, chopped (optional)

directions

I start by seasoning the chicken generously with Cajun seasoning. I heat olive oil in a skillet and cook the chicken until browned and cooked through, then remove it and set aside. In the same skillet, I melt butter and sauté minced garlic until fragrant. I pour in heavy cream and bring it to a simmer before stirring in grated Parmesan cheese until the sauce thickens. Meanwhile, I cook the fettuccine according to package instructions and drain it. I toss the pasta and chicken in the creamy sauce, seasoning with salt and pepper to taste. I garnish with fresh parsley before serving.

Servings and timing

This recipe serves about 4 people. Prep and cooking take around 30–35 minutes.

Variations

Sometimes I add sautéed bell peppers or mushrooms for extra veggies and flavor. Using smoked paprika along with Cajun seasoning adds a smoky depth. I’ve also swapped fettuccine for linguine or penne depending on preference.

storage/reheating

I store leftovers in an airtight container in the fridge for up to 3 days. To reheat, I warm the pasta gently on the stove or microwave, adding a splash of cream or milk to loosen the sauce if needed.

FAQs

Can I use pre-cooked chicken?

Yes, shredded or diced cooked chicken works well; just warm it in the sauce.

How spicy is the Cajun seasoning?

It varies by brand, but I like it medium-spicy. Adjust the amount based on your heat preference.

Can I make this dairy-free?

I substitute heavy cream and Parmesan with dairy-free alternatives like coconut cream and vegan cheese.

What’s the best pasta to use?

I prefer fettuccine for its texture, but any pasta shape you like works well.

Can I freeze leftovers?

I don’t recommend freezing pasta with cream sauces as texture may change, but you can freeze the chicken separately.

Conclusion

Spicy Cajun Chicken Fettuccine in Creamy Garlic Sauce is one of my favorite indulgent dinners that deliver bold flavors and creamy comfort with minimal effort. It’s a perfect meal for spice lovers and pasta fans alike.

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