Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce

Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce is a bold, flavor-packed pasta dish that brings together juicy Cajun-seasoned chicken, tender spaghetti, and a rich, cheesy garlic sauce. I love this dish when I’m craving something comforting but with a spicy kick—it’s creamy, savory, and completely satisfying.

Why You’ll Love This Recipe

I love how this recipe combines the smoky heat of Cajun spices with the smooth, indulgent texture of a garlic mozzarella cream sauce. It’s an easy one-pot pasta that feels restaurant-worthy but comes together in under an hour. Each bite has tender chicken, gooey cheese, and perfectly coated noodles—it’s the kind of dish I make when I want to impress without stress.

Ingredients

(Here’s a tip: Check out the full list of ingredients and measurements in the recipe card below.)

• Spaghetti

• Boneless, skinless chicken breasts or thighs

• Cajun seasoning

• Olive oil or butter (for searing)

• Garlic, minced

• Heavy cream

• Chicken broth

• Mozzarella cheese, shredded

• Parmesan cheese (optional, for extra depth)

• Salt and pepper

• Red pepper flakes (optional, for added spice)

• Fresh parsley (for garnish)

Directions

1. I season the chicken generously with Cajun seasoning on both sides.

2. In a large skillet, I heat olive oil over medium-high heat and sear the chicken until golden and cooked through—about 5–6 minutes per side. I remove the chicken and let it rest before slicing.

3. In the same pan, I lower the heat and sauté the garlic until fragrant, about 1 minute.

4. I pour in the chicken broth and heavy cream, scraping up any bits from the pan.

5. I stir in mozzarella cheese until it melts into a smooth, creamy sauce. If I want a deeper flavor, I add a handful of Parmesan and a pinch of red pepper flakes.

6. While the sauce simmers gently, I cook the spaghetti in salted water until al dente, then drain it.

7. I add the cooked pasta directly into the sauce and toss to coat. I add sliced Cajun chicken on top and spoon more sauce over everything.

8. I finish it off with a sprinkle of parsley and serve hot.

Servings and timing

This recipe serves about 4 people.
Prep time is around 15 minutes, cooking time is about 25–30 minutes, so the total time is under 45 minutes.

Variations

• I sometimes use shrimp instead of chicken for a Cajun seafood version.

• For a lighter option, I use half-and-half instead of heavy cream.

• Adding sautéed bell peppers, onions, or spinach gives the dish extra color and texture.

• Smoked paprika or a squeeze of lemon juice adds extra depth.

• If I want it extra cheesy, I stir in a mix of mozzarella and sharp white cheddar.

storage/reheating

I store leftovers in an airtight container in the fridge for up to 3 days. To reheat, I warm it gently on the stovetop with a splash of cream or broth to loosen the sauce, or microwave in 30-second intervals, stirring in between.

FAQs

Can I use store-bought Cajun seasoning?

Yes, I usually use a blend from the store, but I sometimes mix my own with paprika, cayenne, garlic powder, and herbs.

Will mozzarella melt smoothly into the sauce?

It does if I add it slowly and keep the heat low—it blends well when paired with cream and a bit of broth.

Can I use other pasta shapes?

Definitely. I’ve used penne, fettuccine, and linguine—all work well with the creamy sauce.

Can I make it less spicy?

Yes, I just cut back on the Cajun seasoning or use a milder blend if I want a gentler flavor.

What can I serve with this dish?

I like pairing it with garlic bread, a crisp green salad, or roasted vegetables for a full meal.

Conclusion

Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce is one of those dishes I crave when I want something bold, creamy, and full of flavor. It’s easy to make, rich without being heavy, and always leaves everyone asking for seconds. Whether for a cozy dinner or a dinner-party hit, this pasta never fails to impress.

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